All churches are located in the Roman Catholic Diocese of Charleston which encompasses the entire state of South Carolina.
| Parish Est | Church | City | Current Bldg begun | Weekly collections | Website |
|---|---|---|---|---|---|
| 1789 | St. Mary's Roman Catholic Church (Charleston, South Carolina) | Charleston | |||
| Blessed Sacrament | Charleston | ||||
| 1821 | Cathedral of Saint John the Baptist | Charleston | 1868 | 1 | |
| 1982 | Christ Our King | Mount Pleasant | 1980 | $39,000 | 1 |
| 1999 | Saint Benedict | Mount Pleasant | 2010 | 1 | |
| Saint Joseph's | Charleston | ||||
| 1821 | Saint Patrick's | Charleston | |||
| Stella Maris | Sullivan's Island | ||||
| Our Lady of Mercy | Charleston | ||||
| Nativity | Charleston | ||||
| Saint John's | North Charleston | ||||
| Saint Thomas the Apostle | North Charleston | ||||
| Saint Joseph's | Columbia | ||||
| 1821 | Saint Peter's | Columbia | |||
| 1821 | Saint Mary's | Greenville |